Interactor 1: SCN4A (P35499)
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
Gene: SCN4A

Interactor 2: SCN8A (Q9UQD0)
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)
Gene: SCN8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0006814 - sodium ion transport
GO:0019228 - neuronal action potential
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1836
Hs

1 1980
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024