HitPredict

Interactor 1: COR1A (P31146)
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)
Gene: CORO1A

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DUF1899~WD40, DUF1899~WD40_4, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0006909 - phagocytosis GO:0007015 - actin filament organization GO:0030027 - lamellipodium GO:0051015 - actin filament binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 474
+	Mm
		313368 COR1A_MOUSE (1-461): 5.55e-124: 370: 94.58		COR1C_MOUSE (1-474): 3.61e-136: 402: 97.47
+	Hs
		1246442 CORO6_HUMAN (1-458): 2.43e-119: 358: 67.10		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		724397 COR1A_HUMAN (1-461): 8.48e-124: 369: 100.00		CORO6_HUMAN (2-472): 7.86e-133: 393: 69.00
+	Mm
		313367 COR1A_MOUSE (1-461): 5.55e-124: 370: 94.58		COR1B_MOUSE (2-472): 1.47e-125: 375: 73.11
+	Hs
		1411039 COR1B_HUMAN (1-460): 5.65e-111: 338: 64.05		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		724421 COR1A_HUMAN (1-461): 8.48e-124: 369: 100.00		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Hs
		1246427 CORO6_HUMAN (1-458): 2.43e-119: 358: 67.10		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Mm
		313332 COR1A_MOUSE (1-461): 5.55e-124: 370: 94.58		COR1A_MOUSE (2-467): 2.88e-114: 346: 64.24
+	Hs
		724407 COR1A_HUMAN (1-461): 8.48e-124: 369: 100.00		POC1A_HUMAN (2-294): 1.18e-73: 239: 16.38
+	Hs
		1246423 CORO6_HUMAN (1-458): 2.43e-119: 358: 67.10		POC1A_HUMAN (2-294): 1.18e-73: 239: 16.38
+	Hs
		724411 COR1A_HUMAN (1-461): 8.48e-124: 369: 100.00		POC1B_HUMAN (2-158): 2.99e-36: 141: 20.63
+	Hs
		724415 COR1A_HUMAN (1-461): 8.48e-124: 369: 100.00		COR2A_HUMAN (4-212): 4.19e-25: 110: 10.46
+	Hs
		1411041 COR1B_HUMAN (1-460): 5.65e-111: 338: 64.05		COR2B_HUMAN (4-218): 7.95e-25: 108: 10.57
+	Sc
		1055155 CORO_YEAST (1-443): 9.34e-99: 311: 38.18		CORO_YEAST (2-164): 4.85e-15: 79.6: 12.64
+	Ce
		1018625 CORO_CAEEL (4-449): 1.2e-77: 255: 44.74		LIN53_CAEEL (67-296): 5.82e-21: 96.7: 17.01