HitPredict

Interactor 1: COPB2 (P35606)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)
Gene: COPB2

Interactor 2: COPB (P53618)
Coatomer subunit beta (Beta-coat protein) (Beta-COP)
Gene: COPB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.918

The method score is based on:

Property	Details
Experiments	10921873, 8940050, 9751720, 35271311, 14729954
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Adaptin_N~Coatomer_WDAD, Coatamer_beta_C~Coatomer_WDAD, Coatomer_WDAD~Coatomer_b_Cpla
Common GO terms	GO:0000139 - Golgi membrane GO:0005198 - structural molecule activity GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0006886 - intracellular protein transport and 4 others more... GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006891 - intra-Golgi vesicle-mediated transport GO:0030126 - COPI vesicle coat GO:0030133 - transport vesicle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	906
Hs

1	953

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024