Interactor 1: COPB2 (P35606)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)
Gene: COPB2

Interactor 2: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 35271311, 9751720, 9482852, 10921873, 37071682, 14729954
Identification Methods affinity chromatography technology, pull down, two hybrid, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Coatomer_WDAD~Coatomer_WDAD, COPI_C~Coatomer_WDAD, WD40~WD40
Common GO terms GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 906
Hs

1 1224
+ Bt
+ Hs
+ Dm
+ Sc
+ Sc
+ Hs
+ Hs
+ Ce
+ Zm
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024