HitPredict

Interactor 1: COPB2 (P35606)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)
Gene: COPB2

Interactor 2: ARF5 (P84085)
ADP-ribosylation factor 5
Gene: ARF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006886 - intracellular protein transport GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 180
+	Hs
		725412 COPB2_HUMAN (1-906): 0: 736: 100.00		ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00
+	Hs
		574610 COPB2_HUMAN (1-906): 0: 736: 100.00		ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00
+	Dm
		248478 COPB2_DROME (1-906): 0: 649: 67.65		ARF4_DROME (1-180): 1.02e-77: 231: 83.89
+	Dm
		248479 COPB2_DROME (1-906): 0: 649: 67.65		ARF1_DROME (1-179): 1.52e-66: 202: 79.89
+	Sc
		503103 COPB2_YEAST (3-841): 1.41e-165: 507: 43.87		ARF1_YEAST (1-179): 4.21e-78: 232: 69.83
+	Hs
		863404 COPA_HUMAN (7-900): 1.24e-158: 498: 22.74		ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00
+	Sc
		503120 COPA_YEAST (5-433): 5.89e-67: 245: 14.18		ARF1_YEAST (1-179): 4.21e-78: 232: 69.83
+	Dm
		778388 Q9W0B8_DROME (4-485): 1.99e-50: 195: 12.74		ARF4_DROME (1-180): 1.02e-77: 231: 83.89
+	Dm
		897483 Q9W0B8_DROME (4-485): 1.99e-50: 195: 12.74		ARF1_DROME (1-179): 1.52e-66: 202: 79.89
+	Hs
		574641 WDR5_HUMAN (553-670): 9.92e-20: 93.4: 8.94		ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00
+	Hs
		903100 WDR5_HUMAN (553-670): 9.92e-20: 93.4: 8.94		RAB1A_HUMAN (5-180): 2.05e-68: 208: 20.44
+	Hs
		903508 WDR5_HUMAN (553-670): 9.92e-20: 93.4: 8.94		RAB1B_HUMAN (5-180): 3.59e-68: 207: 20.44