Protein: GP161
G-protein coupled receptor 161 (G-protein coupled receptor RE2)

Gene: GP161, GPR161
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q8N6U8

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005929 - cilium
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0030666 - endocytic vesicle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605749

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

4

4

High-throughput

0.909

High

651687

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

3

4

High-throughput

0.779

High

650561

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

4

High-throughput

0.726

High

1329980

FBW1B
F-box/WD repeat-containing protein 11

2

1

High-throughput

0.726

High

1329981

FBW1A
F-box/WD repeat-containing protein 1A

2

1

High-throughput

0.726

High

1329977

GPR35
G-protein coupled receptor 35

1

18

High-throughput

0.698

High

531109

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

4

2

High-throughput

0.692

High

725418

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

2

High-throughput

0.628

High

835491

CCR2
C-C chemokine receptor type 2

1

19

High-throughput

0.625

High

275903

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

2

1

High-throughput

0.574

High

1032618

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

15

High-throughput

0.574

High

1329971

GOGA5
Golgin subfamily A member 5

2

6

High-throughput

0.574

High

1329972

LMBR1
Limb region 1 protein homolog

2

2

High-throughput

0.574

High

1329979

RTN4
Reticulon-4

2

6

High-throughput

0.574

High

295695

UPK1B
Uroplakin-1b

2

12

High-throughput

0.553

High

1329232

CLD19
Claudin-19

2

1

High-throughput

0.553

High

1329975

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

5

High-throughput

0.553

High

976417

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.536

High

1329976

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

6

High-throughput

0.536

High

1281063

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

2

High-throughput

0.489

High

1143192

PLEC
Plectin

1

1

High-throughput

0.470

High

1329973

CBP
CREB-binding protein

1

1

Small-scale

0.439

High

799295

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.437

High

1329974

SC6A7
Sodium-dependent proline transporter

1

5

High-throughput

0.407

High

642255

COMT
Catechol O-methyltransferase

2

0

High-throughput

0.316

High

914542

EFNA5
Ephrin-A5

2

0

High-throughput

0.316

High

1315500

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

1329978

JPH1
Junctophilin-1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025