Interactor 1: SOAT1 (P35610)
Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)
Gene: SOAT1

Interactor 2: SOAT1 (P35610)
Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)
Gene: SOAT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 32433613, 32433614
Identification Methods electron microscopy 3D single particle reconstruction, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MBOAT~MBOAT
Common GO terms GO:0000062 - fatty-acyl-CoA binding
GO:0004772 - sterol O-acyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008203 - cholesterol metabolic process
and 10 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 550
Hs

1 550
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024