HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26170170, 30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 1133
+	Hs
		967223 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1031360 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		516550 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1136287 PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1271194 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		727042 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		967443 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1031467 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		516698 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1329984 PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05		RC3H2_HUMAN (1-1107): 0: 1494: 51.72