HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SRSF9 (Q13242)
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)
Gene: SRSF9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.894

Property	Details
Experiments	32296183, 35271311, 37071682, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005654 - nucleoplasm GO:0019904 - protein domain specific binding GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 221
+	Hs
		745151 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		992876 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		745135 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF4_HUMAN (15-169): 2.97e-47: 164: 39.52
+	Hs
		1029031 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		993796 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF4_HUMAN (15-169): 2.97e-47: 164: 39.52
+	Hs
		1028634 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF9_HUMAN (1-221): 1.6e-55: 178: 100.00
+	Hs
		1028873 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF5_HUMAN (12-176): 4.58e-54: 176: 35.20
+	Hs
		1029160 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Mm
		857340 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		SRSF1_MOUSE (1-183): 1.13e-57: 184: 69.95
+	Hs
		992743 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		993869 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF4_HUMAN (15-169): 2.97e-47: 164: 39.52
+	Hs
		516744 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		1020247 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Mm
		857324 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		Q542V3_MOUSE (15-169): 1.56e-45: 159: 39.52
+	Hs
		516484 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Mm
		665745 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		PABP1_MOUSE (12-193): 2.05e-42: 153: 20.00
+	Hs
		1020249 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP4_HUMAN (5-104): 2.37e-21: 93.4: 19.80
+	Hs
		680439 TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81		TIAR_HUMAN (103-192): 2.42e-13: 69.9: 11.58
+	Hs
		474019 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PAB4L_HUMAN (108-183): 6.59e-12: 65.7: 14.46