HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31040226, 16356933
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2090 Hs			1 1084
+	Hs
		727329 NU214_HUMAN (1-2090): 0: 691: 100.00		HDAC9_HUMAN (25-1025): 0: 797: 56.25
+	Hs
		727334 NU214_HUMAN (1-2090): 0: 691: 100.00		HDAC5_HUMAN (1-1084): 0: 785: 55.67
+	Hs
		727249 NU214_HUMAN (1-2090): 0: 691: 100.00		HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68
+	Hs
		880872 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC4_HUMAN (1-1072): 0: 974: 100.00
+	Mm
		1112790 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		Q3UJF1_MOUSE (2-1084): 0: 783: 55.84
+	Hs
		1357907 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC5_HUMAN (1-1084): 0: 785: 55.67
+	Mm
		1207909 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		HDAC7_MOUSE (39-1084): 0: 645: 44.47
+	Hs
		1260208 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC7_HUMAN (57-1084): 0: 679: 46.36
+	Hs
		1038852 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68
+	Hs
		1270546 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97
+	Hs
		1270545 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		HDAC2_HUMAN (647-1082): 7.5e-161: 486: 20.97
+	Hs
		1038652 MINT_HUMAN (283-1766): 1.23e-24: 115: 7.56		HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68
+	Hs
		177416 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDAC3_HUMAN (651-1083): 8.19e-150: 455: 20.62
+	Hs
		1056921 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		HDA10_HUMAN (654-1038): 2.39e-140: 439: 37.21
+	Hs
		857974 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68
+	Hs
		1282247 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		HDA10_HUMAN (654-1038): 2.39e-140: 439: 37.21
+	Hs
		1038645 CIC_HUMAN (242-1032): 8.51e-14: 79.9: 9.89		HDAC1_HUMAN (646-1080): 2.95e-163: 492: 21.68
+	Hs
		166514 NACAD_HUMAN (509-1891): 6.3e-30: 132: 9.64		HDAC6_HUMAN (574-1040): 2.26e-108: 368: 32.62
+	Hs
		1056969 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		HDAC8_HUMAN (669-962): 5.23e-24: 107: 27.22
+	Hs
		858045 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		HDAC8_HUMAN (669-962): 5.23e-24: 107: 27.22