HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26496610, 35271311, 37516964
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IBN_N~Nup214_FG
Common GO terms GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2090
Hs

1 876
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+ Tt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024