HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	12917407
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 467
+	Hs
		727240 NU214_HUMAN (1-2090): 0: 691: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		727261 NU214_HUMAN (1-2090): 0: 691: 100.00		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Hs
		727247 NU214_HUMAN (1-2090): 0: 691: 100.00		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58
+	Hs
		1057763 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		950184 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		950252 CIC_HUMAN (242-1032): 8.51e-14: 79.9: 9.89		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		1057764 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Hs
		1035560 CIC_HUMAN (242-1032): 8.51e-14: 79.9: 9.89		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58