HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	26186194, 28514442, 33961781, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 482
+	Hs
		727246 NU214_HUMAN (1-2090): 0: 691: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		727234 NU214_HUMAN (1-2090): 0: 691: 100.00		NTF2_HUMAN (4-139): 2.55e-40: 143: 26.47
+	Hs
		1357447 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030574 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		857971 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1272144 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63