HitPredict

Interactor 1: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Interactor 2: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 770
+	Hs
		727850 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		727851 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		727734 SOX5_HUMAN (1-763): 0: 611: 100.00		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		245569 SOX5_HUMAN (1-763): 0: 611: 100.00		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Dm
		558384 PANG2_DROME (63-630): 4.71e-101: 339: 15.64		GROU_DROME (1-770): 7.74e-141: 433: 59.79
+	Hs
		818792 SOX9_HUMAN (463-700): 7.73e-45: 170: 26.86		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		980665 LEF1_HUMAN (345-654): 1.62e-40: 155: 14.91		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Mm
		653462 LEF1_MOUSE (345-654): 3.6e-40: 154: 15.53		TLE4_MOUSE (1-770): 0: 563: 86.27
+	Hs
		980847 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		245570 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Hs
		980723 LEF1_HUMAN (345-654): 1.62e-40: 155: 14.91		TLE2_HUMAN (1-770): 2e-150: 458: 64.85
+	Dm
		558368 PANG1_DROME (243-630): 8.32e-41: 162: 18.04		GROU_DROME (1-770): 7.74e-141: 433: 59.79
+	Dm
		558392 CIC_DROME (309-664): 1.66e-33: 141: 15.18		GROU_DROME (1-770): 7.74e-141: 433: 59.79
+	Hs
		3239 A0A0S2Z4Q4_HUMAN (99-513): 2.46e-51: 192: 14.02		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		159973 HGS_HUMAN (99-513): 1.79e-48: 185: 14.02		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		245575 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Hs
		903450 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		903155 SRY_HUMAN (543-634): 6.42e-39: 145: 46.74		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		817868 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		196970 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		PRP4_HUMAN (535-761): 1.01e-11: 70.1: 26.92