HitPredict

Interactor 1: SOX6 (P35712)
Transcription factor SOX-6
Gene: SOX6

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 828 Hs			1 440
+	Hs
		727840 SOX6_HUMAN (1-828): 0: 640: 100.00		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		1032565 CIC_HUMAN (323-827): 1.48e-39: 161: 15.33		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		996651 SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		1032636 TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		818014 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		CTBP1_HUMAN (1-440): 0: 547: 100.00
+	Hs
		881308 TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		881305 TF7L1_HUMAN (415-783): 1.27e-35: 145: 12.93		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		881337 SOX13_HUMAN (96-382): 1.45e-35: 145: 36.33		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		817843 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Mm
		1142013 Q60I23_MOUSE (582-707): 1.71e-36: 142: 38.10		Q91YZ2_MOUSE (20-439): 0: 526: 80.95
+	Dm
		220645 Q59DN5_DROME (277-805): 1.99e-50: 189: 24.33		CTBP_DROME (1-361): 1.59e-142: 417: 70.91
+	Hs
		197254 SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02		SERA_HUMAN (29-404): 9.81e-121: 363: 29.23