HitPredict

Interactor 1: MYH11 (P35749)
Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Gene: MYH11

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34349018, 20618440
Identification Methods	cross-linking study, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042470 - melanosome GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 245
+	Hs
		728460 MYH11_HUMAN (1-1972): 0: 1106: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		646685 MYH11_HUMAN (1-1972): 0: 1106: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		728471 MYH11_HUMAN (1-1972): 0: 1106: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		683875 MYH11_HUMAN (1-1972): 0: 1106: 100.00		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		724761 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		725130 MYH10_HUMAN (885-1971): 1.62e-63: 243: 19.36		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		646681 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Mm
		926804 MYH10_MOUSE (912-1972): 5.77e-60: 231: 14.26		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		522602 MYH7_HUMAN (1050-1972): 3.37e-57: 222: 17.60		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		522590 MYH7_HUMAN (1050-1972): 3.37e-57: 222: 17.60		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		927643 MYH2_HUMAN (1220-1972): 1.03e-48: 194: 14.06		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		647370 MYH2_HUMAN (1220-1972): 1.03e-48: 194: 14.06		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		927644 MYH13_HUMAN (734-1600): 4.03e-44: 179: 15.45		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		647371 MYH13_HUMAN (734-1600): 4.03e-44: 179: 15.45		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		502907 MYH3_HUMAN (1414-1972): 3.13e-36: 153: 18.55		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		725128 MYH10_HUMAN (885-1971): 1.62e-63: 243: 19.36		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Mm
		926855 MYH9_MOUSE (1614-1972): 1.89e-19: 98.2: 13.65		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59