HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: TAF12 (Q03761)
Transcription initiation factor TFIID subunit 12 (TAFII-61) (TAFII61) (TAFII-68) (TAFII68) (TBP-associated factor 12) (TBP-associated factor 61 kDa)
Gene: TAF12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.626

Property	Details
Experiments	10783167, 22875988
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 686 Sc			1 539
+	Sc
		969409 RSC4_YEAST (105-686): 4.92e-54: 198: 15.22		TAF12_YEAST (1-539): 0: 554: 100.00
+	Sc
		975956 GCN5_YEAST (124-255): 2.17e-09: 62: 31.82		TAF12_YEAST (1-539): 0: 554: 100.00
+	Hs
		600152 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		TAF12_HUMAN (366-520): 1.09e-51: 175: 36.94
+	Dm
		836510 TAF1_DROME (60-553): 1.09e-55: 208: 14.45		TAF12_DROME (336-520): 1.28e-52: 179: 30.27
+	Hs
		297832 BRWD3_HUMAN (103-567): 1.39e-64: 235: 14.96		K0754_HUMAN (182-450): 4.25e-12: 71.5: 10.79
+	Hs
		631441 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		TAF12_HUMAN (366-520): 1.09e-51: 175: 36.94
+	Hs
		244500 BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71		TAF12_HUMAN (366-520): 1.09e-51: 175: 36.94
+	Hs
		600249 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		RERE_HUMAN (84-410): 2.09e-10: 65.7: 11.11
+	Hs
		631529 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		AUTS2_HUMAN (247-405): 3.49e-21: 100: 11.95
+	Hs
		1017300 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		BPTF_HUMAN (187-407): 6.73e-10: 64.2: 12.22
+	Hs
		631413 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		BPTF_HUMAN (187-407): 6.73e-10: 64.2: 12.22
+	Hs
		244354 BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71		BPTF_HUMAN (187-407): 6.73e-10: 64.2: 12.22
+	Hs
		1262830 PHIP_HUMAN (314-685): 3.59e-20: 97.9: 12.30		RERE_HUMAN (84-410): 2.09e-10: 65.7: 11.11
+	Hs
		998923 EP300_HUMAN (303-417): 1.53e-09: 63.5: 37.61		AUTS2_HUMAN (247-405): 3.49e-21: 100: 11.95
+	Mm
		377 EP300_MOUSE (303-417): 2.19e-09: 63.2: 37.61		AUTS2_MOUSE (247-405): 2.09e-13: 75.4: 12.58
+	Hs
		999163 EP300_HUMAN (303-417): 1.53e-09: 63.5: 37.61		RERE_HUMAN (84-410): 2.09e-10: 65.7: 11.11