Protein: QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)

Gene: QCR2, UQCRC2
Organism: Homo sapiens
Interactions: 216
UniProt ID: P22695

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006119 - oxidative phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

577945

QCR7
Cytochrome b-c1 complex subunit 7

10

4

High-throughput

0.970

High

168965

QCR8
Cytochrome b-c1 complex subunit 8

4

1

High-throughput

0.892

High

651752

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

2

13

High-throughput

0.802

High

559866

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

4

High-throughput

0.789

High

462760

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

3

1

High-throughput

0.662

High

281882

MPPB
Mitochondrial-processing peptidase subunit beta

1

13

High-throughput

0.618

High

470852

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

2

11

High-throughput

0.611

High

651826

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

4

High-throughput

0.611

High

400285

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

0

High-throughput

0.606

High

651859

TCPH
T-complex protein 1 subunit eta

3

2

High-throughput

0.585

High

240764

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

371173

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

395494

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

139683

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

1

High-throughput

0.552

High

156191

CO72L
Cytochrome c oxidase subunit 7A2-like, mitochondrial

1

3

High-throughput

0.536

High

357852

CYB
Cytochrome b

1

3

High-throughput

0.536

High

576086

CX6B1
Cytochrome c oxidase subunit 6B1

1

2

High-throughput

0.536

High

583451

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

High-throughput

0.536

High

640759

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

6

High-throughput

0.536

High

651747

STOM
Stomatin

1

11

High-throughput

0.536

High

651751

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

4

High-throughput

0.536

High

651755

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

9

High-throughput

0.536

High

651800

ICT1
Large ribosomal subunit protein mL62

1

3

High-throughput

0.536

High

651824

COX15
Heme A synthase COX15

1

2

High-throughput

0.536

High

651845

PPM1E
Protein phosphatase 1E

1

3

High-throughput

0.536

High

651858

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

3

High-throughput

0.536

High

651860

SLX1
Structure-specific endonuclease subunit SLX1

1

1

High-throughput

0.536

High

651877

PGES2
Prostaglandin E synthase 2

1

1

High-throughput

0.536

High

651887

QCR9
Cytochrome b-c1 complex subunit 9

1

2

High-throughput

0.536

High

651778

ARF6
ADP-ribosylation factor 6

2

3

High-throughput

0.533

High

193498

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

4

High-throughput

0.521

High

528420

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

3

High-throughput

0.515

High

590366

COX7C
Cytochrome c oxidase subunit 7C, mitochondrial

1

0

High-throughput

0.513

High

651750

AMPL
Cytosol aminopeptidase

1

0

High-throughput

0.513

High

651829

MAPK5
MAP kinase-activated protein kinase 5

1

0

High-throughput

0.513

High

651832

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

651889

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

651798

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.493

High

302751

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.489

High

563202

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.489

High

651754

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.489

High

651759

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.489

High

651786

KPCZ
Protein kinase C zeta type

1

3

High-throughput

0.489

High

651864

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

651896

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.489

High

227371

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.479

High

259446

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

274981

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

5

High-throughput

0.479

High

279649

CISY
Citrate synthase, mitochondrial

1

6

High-throughput

0.479

High

283796

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

2

High-throughput

0.479

High

296195

SCO1
Protein SCO1 homolog, mitochondrial

1

1

High-throughput

0.479

High

315122

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

348365

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.479

High

405792

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

411358

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

505415

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

532360

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

550841

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

587923

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

606228

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

651748

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

651753

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

651760

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

651765

YAP1
Transcriptional coactivator YAP1

1

5

High-throughput

0.479

High

651769

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

651772

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

651777

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.479

High

651782

1433Z
14-3-3 protein zeta/delta

1

2

Small-scale

0.479

High

651788

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

651790

TADBP
TAR DNA-binding protein 43

1

8

Small-scale

0.479

High

651792

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

651795

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

4

High-throughput

0.479

High

651796

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

651797

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

651799

CUL3
Cullin-3

1

3

High-throughput

0.479

High

651802

RBM39
RNA-binding protein 39

1

3

High-throughput

0.479

High

651803

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

651807

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.479

High

651808

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

651813

SMU1
WD40 repeat-containing protein SMU1

1

3

High-throughput

0.479

High

651820

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

651823

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

651830

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.479

High

651831

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

651841

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

651844

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

6

High-throughput

0.479

High

651846

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

651847

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

651849

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

651851

MFRN2
Mitoferrin-2

1

6

High-throughput

0.479

High

651853

OPTN
Optineurin

1

5

High-throughput

0.479

High

651856

CALR3
Calreticulin-3

1

2

High-throughput

0.479

High

651862

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

651863

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

651867

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

3

High-throughput

0.479

High

651875

DUS21
Dual specificity protein phosphatase 21

1

3

High-throughput

0.479

High

651876

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

651880

RTN4
Reticulon-4

1

3

Small-scale

0.479

High

651881

ANLN
Anillin

1

1

High-throughput

0.479

High

651882

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

651884

OCAD1
OCIA domain-containing protein 1

1

1

Small-scale

0.479

High

651886

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

651888

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

651892

FBW1A
F-box/WD repeat-containing protein 1A

1

3

High-throughput

0.479

High

651897

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.479

High

651809

ACAP1
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.470

High

922

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.464

High

137653

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

222723

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

349798

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

482314

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

555337

SKI
Ski oncogene

1

0

Small-scale

0.458

High

587417

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

651756

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

651757

COIL
Coilin

1

0

High-throughput

0.458

High

651758

CAPG
Macrophage-capping protein

1

0

Small-scale

0.458

High

651766

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

651767

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

651768

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

651773

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

651780

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.458

High

651784

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

651787

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

651812

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

651821

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

651828

NLRX1
NLR family member X1

1

0

Small-scale

0.458

High

651869

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

651870

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

651883

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

651890

KCND3
A-type voltage-gated potassium channel KCND3

1

0

Small-scale

0.458

High

651891

HDAC5
Histone deacetylase 5

1

0

High-throughput

0.458

High

651861

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.457

High

135495

DNM1L
Dynamin-1-like protein

1

1

Small-scale

0.445

High

429309

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

529086

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

626068

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

High-throughput

0.445

High

651761

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.445

High

651762

HD
Huntingtin

1

3

High-throughput

0.445

High

651816

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

651854

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

651868

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

651899

X6RFA8
Solute carrier family 25 member 28

1

7

High-throughput

0.445

High

105344

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

125234

LEG9
Galectin-9

1

3

High-throughput

0.437

High

156962

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

345373

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.437

High

420363

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.437

High

651749

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.437

High

651771

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.437

High

651775

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.437

High

651776

RHOA
Transforming protein RhoA

1

5

High-throughput

0.437

High

651779

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.437

High

651781

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.437

High

651785

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

651791

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

2

High-throughput

0.437

High

651805

EMC2
ER membrane protein complex subunit 2

1

3

High-throughput

0.437

High

651810

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

651814

MIDN
Midnolin

1

1

High-throughput

0.437

High

651815

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.437

High

651822

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

651833

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.437

High

651835

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.437

High

651838

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.437

High

651843

DJB14
DnaJ homolog subfamily B member 14

1

2

High-throughput

0.437

High

651848

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

1

High-throughput

0.437

High

651857

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

651866

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.437

High

651872

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.437

High

651873

RHOJ
Rho-related GTP-binding protein RhoJ

1

6

High-throughput

0.437

High

651874

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

651878

AKTIP
AKT-interacting protein

1

1

Small-scale

0.437

High

651879

RHOF
Rho-related GTP-binding protein RhoF

1

6

High-throughput

0.437

High

651894

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.437

High

126996

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

562558

RINI
Ribonuclease inhibitor

1

0

Small-scale

0.426

High

651763

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.426

High

97224

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

651746

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

3

High-throughput

0.407

High

651770

NEK4
Serine/threonine-protein kinase Nek4

1

4

High-throughput

0.407

High

651774

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.407

High

651804

MFS10
Major facilitator superfamily domain-containing protein 10

1

3

High-throughput

0.407

High

651819

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.407

High

651834

CD177
CD177 antigen

1

2

Small-scale

0.407

High

651839

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

651840

MSPD2
Motile sperm domain-containing protein 2

1

2

High-throughput

0.407

High

651842

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.407

High

651893

S35A3
UDP-N-acetylglucosamine transporter

1

1

High-throughput

0.407

High

651794

SLAF1
Signaling lymphocytic activation molecule

2

0

High-throughput

0.318

High

651865

ACE2
Angiotensin-converting enzyme 2

2

0

High-throughput

0.305

High

572777

NCF1
Neutrophil cytosol factor 1

1

0

High-throughput

0.279

Low

651852

FAF2
FAS-associated factor 2

1

0

High-throughput

0.279

Low

651836

Q8N7T0
HCG1820408, isoform CRA_a

1

0

High-throughput

0.268

Low

651871

LHX5
LIM/homeobox protein Lhx5

1

0

High-throughput

0.268

Low

208463

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

319400

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

362770

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

379873

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

415352

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.249

Low

458280

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.249

Low

651764

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.249

Low

651783

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

651789

ANK3
Ankyrin-3

1

0

High-throughput

0.249

Low

651793

CLN3
Battenin

1

0

Small-scale

0.249

Low

651801

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

651806

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

651811

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.249

Low

651817

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

651818

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low

651825

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

651827

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

651837

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

651850

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

651855

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

651885

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

651895

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

651898

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025