HitPredict

Interactor 1: PSC (P35820)
Polycomb group protein Psc (Protein posterior sex combs)
Gene: PSC

Interactor 2: RING1 (Q9VB08)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RING1) (Sex comb extra protein) (dRING protein) (dRING1)
Gene: Sce

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 15280237, 18923078, 25415640, 22491092, 29070704, 32628956, 15147763
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007419 - ventral cord development
GO:0008270 - zinc ion binding
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1601
Dm

1 435
+ Dm
+ Hs
+ Hs
+ Hs
+ Dr
+ Dr
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024