HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 435
+	Hs
		380666 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1205249 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		531617 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		380510 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1140444 K2C79_HUMAN (32-568): 4.69e-80: 264: 55.35		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1192456 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		359525 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		517778 K2C3_HUMAN (27-494): 2.18e-66: 230: 64.32		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00