Protein: HNRH3
Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)

Gene: HNRH3, HNRNPH3
Organism: Homo sapiens
Interactions: 227
UniProt ID: P31942

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

484946

ROA1
Heterogeneous nuclear ribonucleoprotein A1

6

20

Small-scale

0.946

High

728996

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

17

High-throughput

0.806

High

650609

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

20

High-throughput

0.789

High

729051

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

2

20

Small-scale

0.775

High

477928

SNRPA
U1 small nuclear ribonucleoprotein A

1

17

High-throughput

0.691

High

729017

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

17

High-throughput

0.691

High

729049

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.691

High

729078

RBM45
RNA-binding protein 45

1

20

High-throughput

0.691

High

729101

RBM14
RNA-binding protein 14

1

20

High-throughput

0.691

High

729152

STK24
Serine/threonine-protein kinase 24

1

9

High-throughput

0.665

High

728995

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

16

High-throughput

0.656

High

729014

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

17

High-throughput

0.656

High

729041

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

20

High-throughput

0.656

High

729064

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.656

High

729116

RBM4
RNA-binding protein 4

1

20

High-throughput

0.656

High

729005

MATR3
Matrin-3

3

12

High-throughput

0.656

High

371284

MYC
Myc proto-oncogene protein

3

18

High-throughput

0.640

High

172503

XPO1
Exportin-1

1

14

High-throughput

0.618

High

472474

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

729000

FUS
RNA-binding protein FUS

1

20

High-throughput

0.618

High

729024

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

11

High-throughput

0.618

High

729030

EWS
RNA-binding protein EWS

1

16

High-throughput

0.618

High

729038

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.618

High

729039

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

18

High-throughput

0.618

High

729054

RBM39
RNA-binding protein 39

1

20

High-throughput

0.618

High

729055

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

18

High-throughput

0.618

High

729060

ELAV1
ELAV-like protein 1

1

19

High-throughput

0.618

High

729090

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.618

High

729132

MBNL1
Muscleblind-like protein 1

1

5

Small-scale

0.618

High

729140

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.618

High

534696

BIP
Endoplasmic reticulum chaperone BiP

2

12

High-throughput

0.601

High

729004

CCNF
Cyclin-F

2

9

High-throughput

0.601

High

240870

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

259513

BRD4
Bromodomain-containing protein 4

2

13

High-throughput

0.584

High

729130

ANLN
Anillin

2

11

High-throughput

0.584

High

729144

FBW1B
F-box/WD repeat-containing protein 11

2

20

High-throughput

0.584

High

729138

PIM2
Serine/threonine-protein kinase pim-2

1

0

High-throughput

0.584

High

729013

NCBP2
Nuclear cap-binding protein subunit 2

1

20

High-throughput

0.575

High

729025

YBOX1
Y-box-binding protein 1

1

20

Small-scale

0.575

High

729036

NCBP1
Nuclear cap-binding protein subunit 1

1

6

High-throughput

0.575

High

729068

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.575

High

729128

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.575

High

631085

RAB5A
Ras-related protein Rab-5A

2

4

High-throughput

0.571

High

729100

CI072
Guanine nucleotide exchange factor C9orf72

2

8

Small-scale

0.571

High

540818

ERG
Transcriptional regulator ERG

1

5

Small-scale

0.561

High

157002

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.553

High

687901

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.541

High

729022

RS4X
Small ribosomal subunit protein eS4, X isoform

1

3

High-throughput

0.541

High

729093

KAT5
Histone acetyltransferase KAT5

1

7

High-throughput

0.541

High

729114

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.541

High

470876

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.536

High

529190

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.536

High

591498

H2AX
Histone H2AX

1

13

High-throughput

0.536

High

634322

LMNB1
Lamin-B1

1

5

High-throughput

0.536

High

729001

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

13

High-throughput

0.536

High

729002

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.536

High

729020

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

13

High-throughput

0.536

High

729028

CBX1
Chromobox protein homolog 1

1

7

High-throughput

0.536

High

729034

DHX9
ATP-dependent RNA helicase A

1

17

High-throughput

0.536

High

729035

SSRP1
FACT complex subunit SSRP1

1

9

High-throughput

0.536

High

729044

CUL1
Cullin-1

1

20

High-throughput

0.536

High

729045

CUL2
Cullin-2

1

20

High-throughput

0.536

High

729046

CUL3
Cullin-3

1

20

High-throughput

0.536

High

729047

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

729048

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

729061

NEDD8
Ubiquitin-like protein NEDD8

1

8

High-throughput

0.536

High

729063

SMN
Survival motor neuron protein

1

6

Small-scale

0.536

High

729074

COX15
Heme A synthase COX15

1

2

High-throughput

0.536

High

729075

CSN6
COP9 signalosome complex subunit 6

1

6

High-throughput

0.536

High

729077

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

13

High-throughput

0.536

High

729092

CSN5
COP9 signalosome complex subunit 5

1

12

High-throughput

0.536

High

729094

CUL5
Cullin-5

1

20

High-throughput

0.536

High

729099

DCNL1
DCN1-like protein 1

1

6

High-throughput

0.536

High

729106

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

5

High-throughput

0.536

High

729056

CUL7
Cullin-7

2

11

High-throughput

0.533

High

619539

VCAM1
Vascular cell adhesion protein 1

2

11

High-throughput

0.521

High

729122

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

20

High-throughput

0.521

High

729011

ANX11
Annexin A11

1

0

High-throughput

0.518

High

729019

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.515

High

729088

RFFL
E3 ubiquitin-protein ligase rififylin

1

12

High-throughput

0.515

High

608466

DDX5
Probable ATP-dependent RNA helicase DDX5

1

10

High-throughput

0.508

High

729029

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

20

High-throughput

0.508

High

729067

NCBP3
Nuclear cap-binding protein subunit 3

1

5

High-throughput

0.508

High

729080

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

3

High-throughput

0.508

High

729091

DDX17
Probable ATP-dependent RNA helicase DDX17

1

10

High-throughput

0.508

High

729113

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

20

High-throughput

0.508

High

339667

KLF8
Krueppel-like factor 8

1

14

High-throughput

0.500

High

729117

KLF16
Krueppel-like factor 16

1

7

High-throughput

0.500

High

729142

KLF15
Krueppel-like factor 15

1

8

High-throughput

0.500

High

389796

TTHY
Transthyretin

1

1

High-throughput

0.494

High

709241

AA2AR
Adenosine receptor A2a

1

3

High-throughput

0.494

High

729053

DPYL1
Dihydropyrimidinase-related protein 1

1

1

High-throughput

0.494

High

729139

ZMYM2
Zinc finger MYM-type protein 2

1

0

Small-scale

0.493

High

135519

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.489

High

174948

SC16A
Protein transport protein Sec16A

1

2

High-throughput

0.489

High

723981

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.489

High

729027

HTRA4
Serine protease HTRA4

1

4

High-throughput

0.489

High

729057

SPCS2
Signal peptidase complex subunit 2

1

1

High-throughput

0.489

High

125268

LEG9
Galectin-9

1

4

High-throughput

0.479

High

131758

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

14

High-throughput

0.479

High

176152

PER2
Period circadian protein homolog 2

1

2

Small-scale

0.479

High

222756

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

227397

SPOP
Speckle-type POZ protein

1

8

High-throughput

0.479

High

247693

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

262483

MCE1
mRNA-capping enzyme

1

2

High-throughput

0.479

High

285103

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

315182

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

317138

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

6

Small-scale

0.479

High

319443

UFL1
E3 UFM1-protein ligase 1

1

7

High-throughput

0.479

High

324577

HEXI1
Protein HEXIM1

1

8

High-throughput

0.479

High

330691

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

345425

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.479

High

403860

GCR
Glucocorticoid receptor

1

20

Small-scale

0.479

High

405832

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.479

High

487000

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

519782

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

536596

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

550877

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

588011

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

606307

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.479

High

657493

GCSP
Glycine dehydrogenase

1

4

High-throughput

0.479

High

681268

PSA3
Proteasome subunit alpha type-3

1

3

Small-scale

0.479

High

694724

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

713892

PML
Protein PML

1

20

High-throughput

0.479

High

728998

PHB1
Prohibitin 1

1

7

High-throughput

0.479

High

728999

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

729003

BRCA1
Breast cancer type 1 susceptibility protein

1

20

High-throughput

0.479

High

729006

GATA4
Transcription factor GATA-4

1

5

High-throughput

0.479

High

729007

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

729008

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

729010

PPT1
Palmitoyl-protein thioesterase 1

1

5

High-throughput

0.479

High

729012

MECP2
Methyl-CpG-binding protein 2

1

15

High-throughput

0.479

High

729015

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

729016

FOXA1
Hepatocyte nuclear factor 3-alpha

1

4

High-throughput

0.479

High

729021

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

729023

H4
Histone H4

1

6

High-throughput

0.479

High

729026

RNF4
E3 ubiquitin-protein ligase RNF4

1

7

High-throughput

0.479

High

729031

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

729032

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

729037

FOXO1
Forkhead box protein O1

1

10

High-throughput

0.479

High

729040

FOXC1
Forkhead box protein C1

1

10

High-throughput

0.479

High

729043

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

729052

TRI14
Tripartite motif-containing protein 14

1

14

High-throughput

0.479

High

729058

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.479

High

729059

PCBP1
Poly(rC)-binding protein 1

1

20

High-throughput

0.479

High

729062

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.479

High

729066

MIDN
Midnolin

1

3

High-throughput

0.479

High

729071

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

9

High-throughput

0.479

High

729076

ZCH18
Zinc finger CCCH domain-containing protein 18

1

15

High-throughput

0.479

High

729079

PHF6
PHD finger protein 6

1

2

Small-scale

0.479

High

729081

SMC5
Structural maintenance of chromosomes protein 5

1

11

High-throughput

0.479

High

729082

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

7

High-throughput

0.479

High

729084

TNIP2
TNFAIP3-interacting protein 2

1

6

High-throughput

0.479

High

729085

SNIP1
Smad nuclear-interacting protein 1

1

2

High-throughput

0.479

High

729087

DCAF4
DDB1- and CUL4-associated factor 4

1

5

High-throughput

0.479

High

729089

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

729095

FUBP1
Far upstream element-binding protein 1

1

20

High-throughput

0.479

High

729097

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

729103

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

729104

NECD
Necdin

1

11

High-throughput

0.479

High

729107

ANM1
Protein arginine N-methyltransferase 1

1

16

High-throughput

0.479

High

729108

BAG1
BAG family molecular chaperone regulator 1

1

5

High-throughput

0.479

High

729109

MEP50
Methylosome protein WDR77

1

20

High-throughput

0.479

High

729111

OVOL2
Transcription factor Ovo-like 2

1

3

Small-scale

0.479

High

729112

RIOK1
Serine/threonine-protein kinase RIO1

1

10

High-throughput

0.479

High

729115

DDA1
DET1- and DDB1-associated protein 1

1

2

High-throughput

0.479

High

729118

FACD2
Fanconi anemia group D2 protein

1

12

High-throughput

0.479

High

729124

CCDC8
Coiled-coil domain-containing protein 8

1

7

High-throughput

0.479

High

729129

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

729133

RNC
Ribonuclease 3

1

10

High-throughput

0.479

High

729134

RNF12
E3 ubiquitin-protein ligase RLIM

1

8

High-throughput

0.479

High

729135

MKS1
Tectonic-like complex member MKS1

1

2

Small-scale

0.479

High

729137

WWOX
WW domain-containing oxidoreductase

1

4

High-throughput

0.479

High

729141

UBQL2
Ubiquilin-2

1

8

High-throughput

0.479

High

729147

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

729148

SRRM2
Serine/arginine repetitive matrix protein 2

1

19

High-throughput

0.479

High

729149

FBW1A
F-box/WD repeat-containing protein 1A

1

20

High-throughput

0.479

High

729151

AAR2
Protein AAR2 homolog

1

5

High-throughput

0.479

High

692864

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.470

High

729150

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

729033

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

9

High-throughput

0.457

High

429376

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

563285

CFTR
Cystic fibrosis transmembrane conductance regulator

1

11

High-throughput

0.445

High

728997

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

729009

TOB1
Protein Tob1

1

6

Small-scale

0.445

High

729050

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

729070

LITD1
LINE-1 type transposase domain-containing protein 1

1

5

High-throughput

0.445

High

729072

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

729143

DDX41
Probable ATP-dependent RNA helicase DDX41

1

19

High-throughput

0.445

High

183912

S22A2
Solute carrier family 22 member 2

1

1

Small-scale

0.439

High

105431

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

271933

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.437

High

389078

FINC
Fibronectin

1

12

High-throughput

0.437

High

411445

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.437

High

420393

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.437

High

477129

5HT1A
5-hydroxytryptamine receptor 1A

1

2

Small-scale

0.437

High

521219

ARAF
Serine/threonine-protein kinase A-Raf

1

15

High-throughput

0.437

High

565178

ITA4
Integrin alpha-4

1

8

High-throughput

0.437

High

641498

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

14

High-throughput

0.437

High

729042

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

9

High-throughput

0.437

High

729073

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

729086

TIP
T-cell immunomodulatory protein

1

6

High-throughput

0.437

High

729096

CHM4C
Charged multivesicular body protein 4c

1

15

High-throughput

0.437

High

729098

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.437

High

729119

ACE2
Angiotensin-converting enzyme 2

1

5

High-throughput

0.437

High

729120

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

12

High-throughput

0.437

High

729121

TRI31
E3 ubiquitin-protein ligase TRIM31

1

20

High-throughput

0.437

High

729125

MTRFR
Mitochondrial translation release factor in rescue

1

3

High-throughput

0.437

High

729127

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

729131

ANM8
Protein arginine N-methyltransferase 8

1

15

Small-scale

0.437

High

729146

HECD1
E3 ubiquitin-protein ligase HECTD1

1

20

High-throughput

0.437

High

87345

OSCRI
SCRIB overlapping open reading frame protein

1

5

High-throughput

0.407

High

254838

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.407

High

327822

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.407

High

729018

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.407

High

729083

POC5
Centrosomal protein POC5

1

1

High-throughput

0.407

High

729102

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.407

High

729123

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.407

High

729126

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.407

High

729136

USE1
Vesicle transport protein USE1

1

2

Small-scale

0.407

High

729145

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

729110

APOL2
Apolipoprotein L2

1

0

High-throughput

0.269

Low

729069

SPT46
Spermatogenesis-associated protein 46

1

0

High-throughput

0.268

Low

729065

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

729105

CCL13
C-C motif chemokine 13

1

0

High-throughput

0.238

Low

404698

PRIO
Major prion protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025