HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: NUF2 (Q9BZD4)
Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1)
Gene: NUF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 464
+	Mm
		93550 K22E_MOUSE (150-515): 0: 595: 81.69		DESP_MOUSE (132-463): 4.5e-21: 98.9: 14.20
+	Hs
		409220 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		NUF2_HUMAN (1-464): 4.35e-75: 244: 100.00
+	Hs
		409100 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		TGO1_HUMAN (129-463): 1.56e-26: 115: 14.84
+	Hs
		408995 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		DESP_HUMAN (132-463): 3.63e-24: 108: 13.62
+	Hs
		409174 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		DLG5_HUMAN (129-454): 3.27e-21: 99.3: 11.01
+	Hs
		380553 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		DESP_HUMAN (132-463): 3.63e-24: 108: 13.62
+	Hs
		531529 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		DESP_HUMAN (132-463): 3.63e-24: 108: 13.62
+	Hs
		359462 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		DESP_HUMAN (132-463): 3.63e-24: 108: 13.62
+	Hs
		729181 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		MYO5C_HUMAN (129-464): 4.78e-26: 114: 13.30