HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: TRI31 (Q9BZY9)
E3 ubiquitin-protein ligase TRIM31 (EC 2.3.2.27) (Tripartite motif-containing protein 31)
Gene: TRIM31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34650049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 425
+	Hs
		380682 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		TRI31_HUMAN (1-425): 1.72e-96: 297: 100.00
+	Hs
		380552 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		TRI27_HUMAN (1-378): 1.04e-92: 290: 23.56
+	Hs
		380683 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		TRIM7_HUMAN (11-378): 2.51e-85: 271: 20.65
+	Hs
		318774 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		TRI27_HUMAN (1-378): 1.04e-92: 290: 23.56
+	Hs
		531626 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		TRI31_HUMAN (1-425): 1.72e-96: 297: 100.00
+	Hs
		531606 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		TRI58_HUMAN (1-378): 5.74e-91: 285: 24.08
+	Hs
		1062065 K2C72_HUMAN (87-494): 7.09e-77: 255: 61.28		TRI31_HUMAN (1-425): 1.72e-96: 297: 100.00
+	Hs
		536787 K22O_HUMAN (1-506): 1.14e-73: 250: 63.95		TRI27_HUMAN (1-378): 1.04e-92: 290: 23.56
+	Hs
		821686 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		TRIM7_HUMAN (11-378): 2.51e-85: 271: 20.65
+	Hs
		380469 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		TRI26_HUMAN (1-370): 6.92e-83: 265: 26.80
+	Hs
		517736 K2C3_HUMAN (27-494): 2.18e-66: 230: 64.32		TRI27_HUMAN (1-378): 1.04e-92: 290: 23.56
+	Hs
		729168 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		TRIM7_HUMAN (11-378): 2.51e-85: 271: 20.65