HitPredict

Interactor 1: FMR1 (P35922)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) (mFmr1p)
Gene: FMR1

Interactor 2: PRC2C (Q3TLH4)
Protein PRRC2C (BAT2 domain-containing protein 1) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: Prrc2c

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010494 - cytoplasmic stress granule GO:0034063 - stress granule assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 614 Mm			1 2846
+	Hs
		989216 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2C_HUMAN (1-2846): 0: 655: 83.20
+	Mm
		1111986 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2C_MOUSE (1-2846): 0: 763: 100.00
+	Hs
		843980 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2C_HUMAN (1-2846): 0: 655: 83.20
+	Mm
		729531 FMR1_MOUSE (1-614): 0: 1011: 100.00		PRC2B_MOUSE (1-1518): 1.93e-54: 213: 19.44
+	Hs
		988930 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25
+	Mm
		57183 FMR1_MOUSE (1-614): 0: 1011: 100.00		CHD7_MOUSE (90-665): 7.2e-38: 159: 13.95
+	Mm
		729608 FMR1_MOUSE (1-614): 0: 1011: 100.00		NCOR2_MOUSE (688-2838): 9.89e-31: 136: 8.04
+	Hs
		820894 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78
+	Mm
		729533 FMR1_MOUSE (1-614): 0: 1011: 100.00		PRC2A_MOUSE (1167-2839): 1.05e-25: 119: 8.78
+	Hs
		311804 FMR1_HUMAN (1-614): 0: 995: 93.99		TACC2_HUMAN (1319-2821): 5.21e-23: 110: 8.15
+	Mm
		729586 FMR1_MOUSE (1-614): 0: 1011: 100.00		BCL9_MOUSE (46-1208): 5.55e-10: 67.5: 8.07
+	Mm
		729583 FMR1_MOUSE (1-614): 0: 1011: 100.00		ANR17_MOUSE (1699-2153): 9.73e-09: 63.5: 17.15
+	Hs
		843719 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25
+	Mm
		1142852 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2B_MOUSE (1-1518): 1.93e-54: 213: 19.44
+	Hs
		820851 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78
+	Mm
		1142913 FXR1_MOUSE (1-334): 0: 589: 73.65		NCOR2_MOUSE (688-2838): 9.89e-31: 136: 8.04
+	Mm
		1142853 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2A_MOUSE (1167-2839): 1.05e-25: 119: 8.78
+	Hs
		311796 FXR1_HUMAN (1-334): 0: 596: 73.95		TACC2_HUMAN (1319-2821): 5.21e-23: 110: 8.15
+	Hs
		844097 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25
+	Hs
		820852 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78