HitPredict

Interactor 1: LDLR (P35951)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Interactor 2: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	10380922, 10827173
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045177 - apical part of cell
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 862 Mm			1 588
+	Hs
		269145 LRP8_HUMAN (2-851): 2.03e-169: 518: 42.53		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		957177 LRP8_HUMAN (2-851): 2.03e-169: 518: 42.53		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		253558 LRP8_HUMAN (2-851): 2.03e-169: 518: 42.53		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11
+	Mm
		69879 B1AXJ3_MOUSE (2-231): 3.58e-29: 126: 29.83		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		269133 VLDLR_HUMAN (148-644): 5.1e-33: 139: 20.97		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Mm
		956222 VLDLR_MOUSE (198-425): 4.08e-19: 94.9: 20.21		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Mm
		956234 LRP8_MOUSE (190-390): 1.65e-15: 83.3: 23.90		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		269114 LDLR_HUMAN (1-197): 3.77e-15: 82.2: 19.51		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		269134 LRP2_HUMAN (678-845): 3.48e-11: 69.5: 14.20		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		269141 LRP1_HUMAN (24-197): 1.1e-09: 64.9: 23.20		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		351073 LDLR_HUMAN (1-197): 3.77e-15: 82.2: 19.51		ARH_HUMAN (11-271): 2.37e-48: 172: 18.35
+	Hs
		957612 LRP2_HUMAN (678-845): 3.48e-11: 69.5: 14.20		ARH_HUMAN (11-271): 2.37e-48: 172: 18.35
+	Hs
		957621 LRP2_HUMAN (678-845): 3.48e-11: 69.5: 14.20		ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81
+	Hs
		351065 LDLR_HUMAN (1-197): 3.77e-15: 82.2: 19.51		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		270287 LRP6_HUMAN (5-106): 1.14e-11: 71: 30.48		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		957165 LRP2_HUMAN (678-845): 3.48e-11: 69.5: 14.20		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Ce
		60773 LRP_CAEEL (157-419): 1.5e-13: 77.6: 22.26		A5JYR4_CAEEL (2-386): 2.33e-36: 144: 23.06
+	Hs
		957171 LRP1_HUMAN (24-197): 1.1e-09: 64.9: 23.20		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		253552 LRP2_HUMAN (678-845): 3.48e-11: 69.5: 14.20		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11
+	Hs
		253555 LRP1_HUMAN (24-197): 1.1e-09: 64.9: 23.20		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11