Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR
Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18936167 |
| Identification Methods | biochemical, phosphatase assay, coimmunoprecipitation, pull down |
| Interaction Type | dephosphorylation reaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | I-set~fn3, fn3~ig, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase |
| Common GO terms | GO:0001525 - angiogenesis GO:0001570 - vasculogenesis GO:0005886 - plasma membrane GO:0043235 - receptor complex GO:0043410 - positive regulation of MAPK cascade and 3 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
