Protein: ARL2
ADP-ribosylation factor-like protein 2

Gene: ARL2
Organism: Homo sapiens
Interactions: 90
UniProt ID: P36404

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

783133

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

11

1

Small-scale

0.983

High

231376

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

10

4

Small-scale

0.981

High

783096

U119A
Protein unc-119 homolog A

7

4

Small-scale

0.972

High

783118

CFA36
Cilia- and flagella-associated protein 36

3

3

High-throughput

0.861

High

783122

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

2

6

High-throughput

0.811

High

783120

TBCD
Tubulin-specific chaperone D

5

3

Small-scale

0.721

High

65999

U119B
Protein unc-119 homolog B

1

4

High-throughput

0.691

High

783081

ARL3
ADP-ribosylation factor-like protein 3

1

18

High-throughput

0.691

High

639359

5NTD
5'-nucleotidase

3

1

High-throughput

0.667

High

783098

TBB2A
Tubulin beta-2A chain

3

11

High-throughput

0.667

High

783121

TBB2B
Tubulin beta-2B chain

3

11

High-throughput

0.667

High

457267

TBB5
Tubulin beta chain

3

11

High-throughput

0.662

High

58708

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

2

5

High-throughput

0.628

High

407995

TBB4A
Tubulin beta-4A chain

2

10

High-throughput

0.628

High

783092

TBB4B
Tubulin beta-4B chain

2

11

High-throughput

0.628

High

261377

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

6

High-throughput

0.621

High

783109

WDR17
WD repeat-containing protein 17

1

11

High-throughput

0.618

High

783080

ARL2
ADP-ribosylation factor-like protein 2

1

18

High-throughput

0.618

High

783124

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

783116

LHX4
LIM/homeobox protein Lhx4

2

0

High-throughput

0.580

High

142289

PEX7
Peroxisomal targeting signal 2 receptor

1

11

High-throughput

0.575

High

488296

PPBI
Intestinal-type alkaline phosphatase

2

1

High-throughput

0.574

High

783104

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

11

High-throughput

0.574

High

436624

KPCB
Protein kinase C beta type

2

4

High-throughput

0.571

High

421613

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.536

High

729647

1433B
14-3-3 protein beta/alpha

1

13

High-throughput

0.536

High

783086

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

783090

1433Z
14-3-3 protein zeta/delta

1

13

High-throughput

0.536

High

783094

1433F
14-3-3 protein eta

1

13

High-throughput

0.536

High

783101

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

4

High-throughput

0.536

High

783103

TBB8
Tubulin beta-8 chain

1

11

High-throughput

0.536

High

783127

TBC23
TBC1 domain family member 23

1

7

High-throughput

0.536

High

388160

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

783105

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

783110

LMBL4
Lethal(3)malignant brain tumor-like protein 4

1

0

High-throughput

0.513

High

783130

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.513

High

389101

FINC
Fibronectin

1

5

High-throughput

0.489

High

614661

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

5

High-throughput

0.489

High

172031

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

6

High-throughput

0.479

High

227406

SPOP
Speckle-type POZ protein

1

3

High-throughput

0.479

High

240923

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

279674

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

400394

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

16

High-throughput

0.479

High

407401

K2C1
Keratin, type II cytoskeletal 1

1

4

High-throughput

0.479

High

470885

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

4

High-throughput

0.479

High

475534

K1C19
Keratin, type I cytoskeletal 19

1

8

High-throughput

0.479

High

588062

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

650620

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

5

High-throughput

0.479

High

694775

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

771960

K1C9
Keratin, type I cytoskeletal 9

1

8

High-throughput

0.479

High

783082

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

783083

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

783084

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.479

High

783085

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

2

High-throughput

0.479

High

783089

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

783093

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

783095

TIF1B
Transcription intermediary factor 1-beta

1

7

High-throughput

0.479

High

783097

CUL3
Cullin-3

1

4

High-throughput

0.479

High

783100

ZN638
Zinc finger protein 638

1

1

High-throughput

0.479

High

783102

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.479

High

783106

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

783117

OPTN
Optineurin

1

17

High-throughput

0.479

High

783119

SCLT1
Sodium channel and clathrin linker 1

1

10

High-throughput

0.479

High

783123

OSBL2
Oxysterol-binding protein-related protein 2

1

4

High-throughput

0.479

High

783114

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

5

High-throughput

0.470

High

519062

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

783088

H4
Histone H4

1

0

High-throughput

0.458

High

783108

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

783111

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

783113

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.458

High

783112

BSND
Barttin

1

1

Small-scale

0.457

High

330061

VENTX
Homeobox protein VENTX

1

8

High-throughput

0.445

High

598698

ANFB
Natriuretic peptides B

1

2

High-throughput

0.445

High

783087

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

3

Small-scale

0.445

High

783091

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

3

Small-scale

0.445

High

783126

DDX28
Probable ATP-dependent RNA helicase DDX28

1

6

High-throughput

0.445

High

783128

ATD3A
ATPase family AAA domain-containing protein 3A

1

11

High-throughput

0.445

High

783129

SCN3B
Sodium channel regulatory subunit beta-3

1

7

High-throughput

0.445

High

783132

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

3

Small-scale

0.445

High

417979

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

8

High-throughput

0.437

High

783115

RYR2
Ryanodine receptor 2

1

3

High-throughput

0.437

High

783099

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

Small-scale

0.426

High

619558

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.407

High

783107

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

11

High-throughput

0.407

High

783131

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.407

High

783134

NPTN
Neuroplastin

1

8

High-throughput

0.407

High

51309

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

389716

FETUA
Alpha-2-HS-glycoprotein

1

0

High-throughput

0.249

Low

783125

ST20
Suppressor of tumorigenicity 20 protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025