Interactor 1: VGFR1 (P35969)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT)
Gene: Flt1

Interactor 2: NRP1 (P97333)
Neuropilin-1 (A5 protein) (CD antigen CD304)
Gene: NRP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10842181, 23452854
Identification Methods pull down, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MAM~ig
Common GO terms GO:0001525 - angiogenesis
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0002040 - sprouting angiogenesis
GO:0005021 - vascular endothelial growth factor receptor activity
GO:0005886 - plasma membrane
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1333
Mm

1 923
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024