HitPredict

Interactor 1: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Interactor 2: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 28539385, 32296183, 33961781, 35271311, 37071682, 20810900, 22275368, 28292943, 10625621, 34349018, unassigned1304, 22901813
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, pull down, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 433
Hs

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Last updated: 15 Jul 2024