HitPredict

Interactor 1: MYO3 (P36006)
Myosin-3 (Actin-dependent myosin-I MYO3) (Class I unconventional myosin MYO3) (Type I myosin MYO3)
Gene: MYO3

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.868

The method score is based on:

Property Details
Experiments 11743162, 16554755, 19841731
Identification Methods two hybrid, affinity chromatography technology, two hybrid pooling approach, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Myosin_head~Myosin_head, SH3_1~SH3_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1272
Sc

1 1219
+ Zm
+ Sc
+ At
+ Sc
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Mm

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Last updated: 15 Jul 2024