Interactor 1: NOTC1 (Q01705)
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: Notch1

Interactor 2: PSN2 (Q61144)
Presenilin-2 (PS-2) (EC 3.4.23.-) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Gene: Psen2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 11518718
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
and 8 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 2531
Mm

1 448
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Dm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024