Interactor 1: DHR2 (P36009)
Probable ATP-dependent RNA helicase DHR2 (EC 3.6.4.13) (DEAH box RNA helicase DHR2) (Helicase JA2)
Gene: DHR2

Interactor 2: PRP43 (P53131)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (EC 3.6.4.13) (Helicase JA1)
Gene: PRP43

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.752

The method score is based on:

Property Details
Experiments 29054886
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2, DEAD~Helicase_C, HA2~Helicase_C, HA2~OB_NTP_bind, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, OB_NTP_bind~OB_NTP_bind
Common GO terms GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0004386 - helicase activity
GO:0005524 - ATP binding
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 735
Sc

1 767
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Sc
+ Sc
+ Ce
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024