HitPredict

Interactor 1: YPT52 (P36018)
GTP-binding protein YPT52
Gene: YPT52

Interactor 2: GDI1 (P39958)
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
Gene: GDI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.80	0.849

Property	Details
Experiments	11805837, 11805826, 11785952, 22157956, 16429126, 37968396
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification, two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Sc			1 451
+	Hs
		678330 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838605 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Mm
		838709 RAB1A_MOUSE (4-233): 1.77e-75: 228: 28.70		GDIA_MOUSE (6-450): 0: 653: 54.04
+	Hs
		678344 RAB1A_HUMAN (4-233): 1.77e-75: 228: 28.70		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		678394 RAB1B_HUMAN (4-233): 2.77e-75: 227: 29.57		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838625 RAB1A_HUMAN (4-233): 1.77e-75: 228: 28.70		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		838683 RAB1B_HUMAN (4-233): 2.77e-75: 227: 29.57		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		678343 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Dm
		185501 O18332_DROME (4-233): 1.38e-74: 226: 30.87		Q9VLB7_DROME (6-448): 0: 625: 53.38
+	Sc
		699420 YPT52_YEAST (1-234): 2.89e-76: 231: 100.00		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	At
		1228188 RAA1F_ARATH (4-234): 1.15e-74: 227: 31.47		REP_ARATH (3-444): 1.06e-107: 331: 21.67
+	At
		656917 RAE1C_ARATH (4-233): 3.16e-74: 226: 30.87		REP_ARATH (3-444): 1.06e-107: 331: 21.67
+	Hs
		622565 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642710 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622577 RAB1A_HUMAN (4-233): 1.77e-75: 228: 28.70		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642723 RAB1A_HUMAN (4-233): 1.77e-75: 228: 28.70		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622619 RAB1B_HUMAN (4-233): 2.77e-75: 227: 29.57		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642743 RAB1B_HUMAN (4-233): 2.77e-75: 227: 29.57		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622576 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642722 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71