Interactor 1: EMC3 (P36039)
ER membrane protein complex subunit 3 (Altered inheritance rate of mitochondria protein 27)
Gene: EMC3

Interactor 2: EMC4 (P53073)
ER membrane protein complex subunit 4
Gene: EMC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 25313861, 37968396
Identification Methods bimolecular fluorescence complementation, protein complementation assay, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DUF1077~EMC3_TMCO1
Common GO terms GO:0006644 - phospholipid metabolic process
GO:0015914 - phospholipid transport
GO:0034975 - protein folding in endoplasmic reticulum
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0072546 - EMC complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 253
Sc

1 190
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024