HitPredict

Interactor 1: SET3 (P36124)
SET domain-containing protein 3
Gene: SET3

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 751 Sc			1 889
+	Sc
		696198 SET3_YEAST (1-751): 0: 685: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		733289 SET3_YEAST (1-751): 0: 685: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		1067123 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		331815 NSD2_HUMAN (122-556): 4.59e-74: 264: 13.29		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		1067099 NSD1_HUMAN (122-556): 1.12e-72: 260: 13.59		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		975255 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		1067127 SETD5_HUMAN (36-750): 1.6e-50: 193: 13.49		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Mm
		1111947 NSD2_MOUSE (122-556): 4.95e-74: 264: 13.29		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Hs
		631576 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		847072 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		331723 NSD2_HUMAN (122-556): 4.59e-74: 264: 13.29		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		846864 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		SMCA2_HUMAN (9-150): 9.42e-28: 123: 24.07
+	Hs
		244897 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		243764 NSD2_HUMAN (122-556): 4.59e-74: 264: 13.29		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1123391 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		BRDT_HUMAN (1-263): 1.78e-25: 115: 13.11
+	Mm
		1207357 NSD2_MOUSE (122-556): 4.95e-74: 264: 13.29		BRD4_MOUSE (2-329): 7.51e-26: 117: 12.31
+	Hs
		846753 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		SMCA2_HUMAN (9-150): 9.42e-28: 123: 24.07
+	Hs
		244315 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		600130 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		TAF1_HUMAN (3-203): 4.84e-19: 95.2: 11.82
+	Hs
		244906 SETD5_HUMAN (36-750): 1.6e-50: 193: 13.49		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65