Protein: OPRD
Delta-type opioid receptor (D-OR-1) (DOR-1)

Gene: OPRD, OPRD1
Organism: Homo sapiens
Interactions: 42
UniProt ID: P41143

Gene Ontology (top 5):
GO:0004985 - G protein-coupled opioid receptor activity
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

732458

ARRB2
Beta-arrestin-2

2

12

Small-scale

0.768

High

770827

OPRM
Mu-type opioid receptor

2

13

Small-scale

0.754

High

458312

ADRB2
Beta-2 adrenergic receptor

1

16

Small-scale

0.724

High

832359

OPRD
Delta-type opioid receptor

1

16

Small-scale

0.724

High

832360

ARRB1
Beta-arrestin-1

1

12

Small-scale

0.724

High

418612

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

17

Small-scale

0.618

High

482584

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

17

Small-scale

0.618

High

726287

SSR4
Somatostatin receptor type 4

1

16

Small-scale

0.618

High

832363

SMAGP
Small cell adhesion glycoprotein

2

1

High-throughput

0.606

High

832381

S12A7
Solute carrier family 12 member 7

2

12

High-throughput

0.606

High

832367

GASP1
G-protein coupled receptor-associated sorting protein 1

2

6

Small-scale

0.597

High

832372

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

832380

S13A4
Solute carrier family 13 member 4

2

0

High-throughput

0.580

High

832366

CTXN3
Cortexin-3

2

1

High-throughput

0.553

High

832376

RPRM
Protein reprimo

2

2

High-throughput

0.553

High

598025

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

20

Small-scale

0.536

High

131788

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

Small-scale

0.479

High

135537

DNM1L
Dynamin-1-like protein

1

1

Small-scale

0.479

High

256449

TOM1
Target of Myb1 membrane trafficking protein

1

2

Small-scale

0.479

High

329433

EPN2
Epsin-2

1

2

Small-scale

0.479

High

390481

TFR1
Transferrin receptor protein 1

1

1

Small-scale

0.479

High

764203

CXA4
Gap junction alpha-4 protein

1

5

Small-scale

0.479

High

832364

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

Small-scale

0.479

High

832368

WLS
Protein wntless homolog

1

5

Small-scale

0.479

High

832375

RBNS5
Rabenosyn-5

1

4

Small-scale

0.479

High

832377

MYOF
Myoferlin

1

3

Small-scale

0.479

High

832378

ITSN2
Intersectin-2

1

1

Small-scale

0.479

High

832379

VAPA
Vesicle-associated membrane protein-associated protein A

1

6

Small-scale

0.479

High

832373

SORT
Sortilin

1

0

Small-scale

0.458

High

698453

CALX
Calnexin

1

2

Small-scale

0.457

High

211544

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

7

Small-scale

0.437

High

832361

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

5

Small-scale

0.437

High

832362

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

Small-scale

0.437

High

832369

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

7

Small-scale

0.437

High

832370

DOK4
Docking protein 4

1

3

Small-scale

0.437

High

832371

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

2

Small-scale

0.437

High

832374

SNAG
Gamma-soluble NSF attachment protein

1

2

Small-scale

0.437

High

832382

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

3

Small-scale

0.437

High

165539

SCAM3
Secretory carrier-associated membrane protein 3

1

0

Small-scale

0.249

Low

239019

ZNRD2
Protein ZNRD2

1

0

Small-scale

0.249

Low

832365

SPCS2
Signal peptidase complex subunit 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025