Interactor 1: SPC34 (P36131)
DASH complex subunit SPC34 (34 kDa spindle pole component protein) (Outer kinetochore protein SPC34)
Gene: SPC34

Interactor 2: DAM1 (P53267)
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)
Gene: DAM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.928

The method score is based on:

Property Details
Experiments 11283351, 12925767, 34313341, 20730753, 25382489, 14627828, 15640796, 17634282, 18364702, 17460120, 33851957, 37968396
Identification Methods two hybrid pooling approach, pull down, two hybrid, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DASH_Dam1~DASH_Spc34
Common GO terms GO:0005737 - cytoplasm
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex
GO:0051301 - cell division
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024