HitPredict

Interactor 1: SPC34 (P36131)
DASH complex subunit SPC34 (34 kDa spindle pole component protein) (Outer kinetochore protein SPC34)
Gene: SPC34

Interactor 2: DAD4 (P69851)
DASH complex subunit DAD4 (DUO1 and DAM1-interacting protein 4) (Helper of ASK1 protein 2) (Outer kinetochore protein DAD4)
Gene: DAD4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.55	0.708

The method score is based on:

Property	Details
Experiments	25382489, 15640796, 18364702, 33851957, 16554755, 17634282, 37968396
Identification Methods	pull down, biochemical, affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	direct interaction, association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008608 - attachment of spindle microtubules to kinetochore GO:0031116 - positive regulation of microtubule polymerization GO:0042729 - DASH complex GO:0051301 - cell division and 4 others more... GO:0051987 - positive regulation of attachment of spindle microtubules to kinetochore GO:0072686 - mitotic spindle GO:1990758 - mitotic sister chromatid biorientation GO:1990976 - protein transport along microtubule to mitotic spindle pole body
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024