Interactor 1: ACHA7 (P36544)
Neuronal acetylcholine receptor subunit alpha-7
Gene: CHRNA7

Interactor 2: CRFM7 (Q494W8)
CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10)
Gene: CHRFAM7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28750690
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0015464 - acetylcholine receptor activity
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
GO:0042166 - acetylcholine binding
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 502
Hs

1 412
+ Rn
+ Rn
+ Hs
+ Gg
+ Gg
+ Gg
+ Dm
+ Rn
+ Hs
+ Mm
+ Gg
+ Gg
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024