HitPredict

Interactor 1: RL4 (P36578)
Large ribosomal subunit protein uL4 (60S ribosomal protein L1) (60S ribosomal protein L4)
Gene: RPL4

Interactor 2: RL18 (Q07020)
Large ribosomal subunit protein eL18 (60S ribosomal protein L18)
Gene: RPL18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.945

The method score is based on:

Property	Details
Experiments	30021884, 35271311, 37071682, 33961781, 34349018, 35235311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Ribos_L4_asso_C~Ribosomal_L18, Ribosomal_L18~Ribosomal_L4
Common GO terms	GO:0002181 - cytoplasmic translation GO:0003723 - RNA binding GO:0003735 - structural constituent of ribosome GO:0005634 - nucleus GO:0005730 - nucleolus and 8 others more... GO:0005737 - cytoplasm GO:0005791 - rough endoplasmic reticulum GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0006412 - translation GO:0016020 - membrane GO:0022625 - cytosolic large ribosomal subunit GO:0022626 - cytosolic ribosome
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	427
Hs

1	188

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024