Protein: ACT3
Actin-57B (EC 3.6.4.-)

Gene: ACT3, Act57B
Organism: Drosophila melanogaster
Interactions: 60
UniProt ID: P53501

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0015629 - actin cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921001

Q9VPX6
Adenylyl cyclase-associated protein

3

20

High-throughput

0.834

High

386974

ACT2
Actin-42A

2

18

High-throughput

0.767

High

387037

ACT4
Actin, larval muscle

2

18

High-throughput

0.767

High

920976

ACT6
Actin, indirect flight muscle

2

19

High-throughput

0.767

High

52510

A1Z6Z9
Dilute class unconventional myosin, isoform A

2

11

High-throughput

0.737

High

852907

ARP2
Actin-related protein 2

2

16

High-throughput

0.737

High

920996

Q9VMH2
Actin-related protein 2/3 complex subunit 4

2

2

High-throughput

0.737

High

756733

FAS2
Fasciclin-2

1

1

High-throughput

0.691

High

875077

CAPZB
F-actin-capping protein subunit beta

2

4

High-throughput

0.659

High

921009

CAPZA
F-actin-capping protein subunit alpha

2

9

High-throughput

0.659

High

52997

A1Z7J1
Sticks and stones, isoform A

1

2

High-throughput

0.656

High

920986

Q9I7J0
GH21596p

1

20

High-throughput

0.656

High

118030

M9MS50
non-specific serine/threonine protein kinase

1

11

High-throughput

0.621

High

561565

SPTCA
Spectrin alpha chain

1

20

Small-scale

0.618

High

736416

ARP3
Actin-related protein 3

1

18

High-throughput

0.618

High

920984

AKT1
RAC serine/threonine-protein kinase

1

11

High-throughput

0.618

High

920988

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

4

High-throughput

0.618

High

921008

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

14

High-throughput

0.618

High

921000

Q9VNV0
non-specific serine/threonine protein kinase

1

10

High-throughput

0.590

High

534418

ACT1
Actin-5C

1

18

High-throughput

0.575

High

920990

Q9VF28
Actin-related protein 2/3 complex subunit 3

1

3

High-throughput

0.575

High

920993

EFHD2
EF-hand domain-containing protein D2 homolog

2

3

High-throughput

0.571

High

357019

O97182
Actin-related protein 2/3 complex subunit

1

10

High-throughput

0.553

High

920992

ARPC2
Actin-related protein 2/3 complex subunit 2

1

2

High-throughput

0.553

High

304945

CRY1
Cryptochrome-1

1

1

Small-scale

0.552

High

920999

GRCR1
Glutaredoxin domain-containing cysteine-rich protein CG31559

2

6

High-throughput

0.542

High

921011

GRCR2
Glutaredoxin domain-containing cysteine-rich protein CG12206

2

6

High-throughput

0.542

High

874956

PRS4
26S proteasome regulatory subunit 4

1

2

High-throughput

0.508

High

921005

Q9VVQ1
Allatostatin C receptor 1

1

6

High-throughput

0.508

High

921010

Q9W3V9
Nuclear transcription factor Y subunit gamma

1

3

High-throughput

0.508

High

920995

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.486

High

68706

A8JQV1
Uncharacterized protein, isoform C

1

13

High-throughput

0.479

High

669585

OSKA
Maternal effect protein oskar

1

4

Small-scale

0.479

High

920975

TBB2
Tubulin beta-2 chain

1

3

High-throughput

0.479

High

920981

CALYP
Ubiquitin carboxyl-terminal hydrolase calypso

1

11

Small-scale

0.479

High

920985

Q8T0T2
GH09296p

1

5

Small-scale

0.479

High

920989

ANLN
Anillin

1

10

Small-scale

0.479

High

920994

Q9VKQ5
GEO07393p1

1

2

High-throughput

0.479

High

920997

ORCO
Odorant receptor coreceptor

1

2

Small-scale

0.479

High

920998

RHEB
GTP-binding protein Rheb homolog

1

4

High-throughput

0.479

High

921003

PYRG
CTP synthase

1

2

High-throughput

0.479

High

921004

OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.479

High

921012

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

624293

CI
Transcriptional activator cubitus interruptus

1

4

High-throughput

0.464

High

195012

O16043
Anon1A4

1

0

High-throughput

0.458

High

476916

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.458

High

921002

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.458

High

920979

Q4V467
IP10845p

1

13

High-throughput

0.445

High

920978

Q3YBY4
Virus-induced 1

1

1

High-throughput

0.439

High

920987

Q9N6D8
GH11591p

1

5

High-throughput

0.439

High

920983

LASP1
LIM and SH3 domain protein Lasp

1

20

Small-scale

0.437

High

921007

PGPLE
Peptidoglycan-recognition protein LE

1

5

High-throughput

0.437

High

920977

Q0E8R1
FI07211p

1

1

High-throughput

0.417

High

304766

O76928
Carmine, isoform A

1

2

High-throughput

0.407

High

920982

Q7KSK8
BcDNA.GH09045

1

3

High-throughput

0.407

High

921006

Q9VXN3
LD07988p

1

12

High-throughput

0.407

High

787605

HYI
Putative hydroxypyruvate isomerase

2

0

High-throughput

0.298

High

892323

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.265

Low

920980

Q7K2K2
FI04612p

1

0

High-throughput

0.249

Low

920991

Q9VG60
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025