HitPredict

Interactor 1: PCK1 (P36582)
Protein kinase C-like 1 (EC 2.7.11.13)
Gene: PCK1

Interactor 2: RHO5 (Q9HE04)
GTP-binding protein rho5
Gene: RHO5

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25651781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, HR1~Ras, Pkinase~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032153 - cell division site
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 988 Sp			1 200
+	Sp
		736851 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO1_SCHPO (1-200): 3.42e-80: 239: 85.64
+	Sp
		736850 PCK1_SCHPO (1-988): 0: 895: 100.00		CDC42_SCHPO (1-200): 2.18e-78: 234: 48.50
+	Sp
		736852 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO2_SCHPO (5-180): 2.89e-76: 229: 56.82
+	Sp
		736855 PCK1_SCHPO (1-988): 0: 895: 100.00		RHO4_SCHPO (3-175): 2.08e-74: 224: 61.71
+	Sp
		736859 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO1_SCHPO (1-200): 3.42e-80: 239: 85.64
+	Sp
		736865 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO5_SCHPO (1-200): 3.5e-80: 238: 100.00
+	Sp
		736857 PCK2_SCHPO (1-984): 0: 802: 45.38		CDC42_SCHPO (1-200): 2.18e-78: 234: 48.50
+	Sp
		736860 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO2_SCHPO (5-180): 2.89e-76: 229: 56.82
+	Sp
		736864 PCK2_SCHPO (1-984): 0: 802: 45.38		RHO4_SCHPO (3-175): 2.08e-74: 224: 61.71
+	Hs
		915706 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOB_HUMAN (5-183): 8.33e-93: 270: 67.60
+	Hs
		925308 PKN2_HUMAN (2-987): 0: 649: 23.33		RAC1_HUMAN (7-200): 4.35e-83: 246: 54.64
+	Hs
		900514 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOA_HUMAN (1-200): 8.79e-81: 240: 64.00
+	Hs
		545401 PKN2_HUMAN (2-987): 0: 649: 23.33		RAC2_HUMAN (7-200): 2.07e-79: 236: 52.06
+	Hs
		436326 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOC_HUMAN (1-200): 1.11e-78: 235: 63.00
+	Hs
		894056 PKN2_HUMAN (2-987): 0: 649: 23.33		CDC42_HUMAN (6-200): 1.39e-78: 234: 51.80
+	Hs
		951021 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOG_HUMAN (6-200): 2e-77: 231: 52.31
+	Hs
		120458 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOD_HUMAN (8-180): 4.29e-71: 216: 52.02
+	Hs
		1082036 PKN2_HUMAN (2-987): 0: 649: 23.33		RHOF_HUMAN (8-200): 1.63e-69: 212: 51.81
+	Hs
		681775 AKT1_HUMAN (531-987): 2.71e-154: 466: 37.20		RAC1_HUMAN (7-200): 4.35e-83: 246: 54.64
+	Sc
		419673 KPC1_YEAST (598-988): 1.8e-133: 432: 54.22		RHO1_YEAST (4-181): 5.87e-95: 276: 78.09