HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 30472188
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 504
+	Hs
		125313 PP1A_HUMAN (1-323): 0: 579: 90.66		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125314 PP1B_HUMAN (1-322): 0: 560: 86.89		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		808454 PP1A_HUMAN (1-323): 0: 579: 90.66		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808455 PP1B_HUMAN (1-322): 0: 560: 86.89		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		931006 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		808496 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		906120 PP1A_HUMAN (1-323): 0: 579: 90.66		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		906167 PP1A_HUMAN (1-323): 0: 579: 90.66		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61