HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Metallophos
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 377
+	Hs
		737677 PP1G_HUMAN (1-323): 0: 603: 100.00		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		737730 PP1G_HUMAN (1-323): 0: 603: 100.00		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		891662 PP1A_HUMAN (1-323): 0: 579: 90.66		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		905825 PP1A_HUMAN (1-323): 0: 579: 90.66		ACTS_HUMAN (1-377): 0: 599: 98.94
+	Mm
		906230 PP1A_MOUSE (1-323): 0: 579: 90.36		ACTG_MOUSE (4-377): 0: 599: 94.39
+	Hs
		891663 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		906403 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		906406 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		906407 PP1B_HUMAN (1-322): 0: 560: 86.89		ACTS_HUMAN (1-377): 0: 599: 98.94