Protein: APE2
Aminopeptidase 2, mitochondrial (AP-II) (Aminopeptidase II) (EC 3.4.11.-) (YscII)

Gene: APE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P32454

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

544157

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.601

High

736855

MKT1
Post-transcriptional regulator MKT1

2

0

High-throughput

0.585

High

736847

RPN1
26S proteasome regulatory subunit RPN1

2

1

High-throughput

0.571

High

736860

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

523354

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.552

High

526169

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

736838

HSP7F
Heat shock protein homolog SSE1

2

9

High-throughput

0.552

High

604925

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

624983

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.536

High

626649

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.536

High

736851

FHP
Flavohemoprotein

1

2

High-throughput

0.536

High

477529

MYO1
Myosin-1

1

0

Small-scale

0.529

High

622336

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.513

High

437894

KAPC
cAMP-dependent protein kinase type 3

1

2

High-throughput

0.501

High

736852

VHR2
Transcription factor VHR2

1

0

High-throughput

0.493

High

736843

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.486

High

510301

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

670462

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

679482

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

706491

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

726838

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

736841

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.479

High

736872

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

360956

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.458

High

646340

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

736845

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

736848

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

Small-scale

0.458

High

736863

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

736865

COS5
Protein COS5

1

0

High-throughput

0.458

High

736866

HGH1
Protein HGH1

1

0

Small-scale

0.458

High

736868

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

736869

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.458

High

736870

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

0

High-throughput

0.458

High

366970

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.445

High

392410

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

427180

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

450546

FAS1
Fatty acid synthase subunit beta

1

2

High-throughput

0.445

High

453478

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

518238

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.445

High

590570

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

592091

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

598981

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

2

High-throughput

0.445

High

618562

FAS2
Fatty acid synthase subunit alpha

1

2

High-throughput

0.445

High

721770

XPO1
Exportin-1

1

2

High-throughput

0.445

High

736840

PRS7
26S proteasome regulatory subunit 7 homolog

1

8

High-throughput

0.445

High

736842

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.445

High

736844

SYG
Glycine--tRNA ligase 1, mitochondrial

1

2

High-throughput

0.445

High

736846

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.445

High

736853

IMB4
Importin subunit beta-4

1

3

High-throughput

0.445

High

736854

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

736856

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

736861

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.445

High

736867

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.445

High

736874

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

481866

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.437

High

736875

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.437

High

358152

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

364975

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

386625

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

394345

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

434922

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

486087

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

531275

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.426

High

677792

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.426

High

736857

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

736859

ZNF1
Respiratory transcription factor ZNF1

1

0

High-throughput

0.426

High

736876

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.426

High

736871

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

575410

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

3

High-throughput

0.407

High

603432

VATA
V-type proton ATPase catalytic subunit A

1

7

High-throughput

0.407

High

663659

RL24B
Large ribosomal subunit protein eL24B

1

2

High-throughput

0.407

High

736839

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.407

High

736849

TCPD
T-complex protein 1 subunit delta

1

4

High-throughput

0.407

High

736850

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.407

High

736858

GCN20
Protein GCN20

1

4

High-throughput

0.407

High

736862

ARP3
Actin-related protein 3

1

1

High-throughput

0.407

High

736864

BUD4
Bud site selection protein 4

1

0

High-throughput

0.279

Low

736873

YD241
Uncharacterized protein YDL241W

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025