HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17274640
Identification Methods	affinity chromatography technology, antibody array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0007283 - spermatogenesis and 1 others more... GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 233
+	Mm
		926544 PP1G_MOUSE (1-323): 0: 602: 99.69		B2CL1_MOUSE (1-233): 3.12e-94: 277: 97.85
+	Hs
		905852 PP1A_HUMAN (1-323): 0: 579: 90.66		B2CL1_HUMAN (1-233): 2.85e-101: 295: 100.00
+	Mm
		489481 PP1G_MOUSE (1-323): 0: 602: 99.69		BCL2_MOUSE (5-231): 1.12e-75: 230: 42.98
+	Hs
		489378 PP1G_HUMAN (1-323): 0: 603: 100.00		BCL2_HUMAN (5-231): 3.01e-71: 219: 44.16
+	Mm
		489480 PP1A_MOUSE (1-323): 0: 579: 90.36		BCL2_MOUSE (5-231): 1.12e-75: 230: 42.98
+	Hs
		489393 PP1A_HUMAN (1-323): 0: 579: 90.66		BCL2_HUMAN (5-231): 3.01e-71: 219: 44.16
+	Hs
		489394 PP1B_HUMAN (1-322): 0: 560: 86.89		BCL2_HUMAN (5-231): 3.01e-71: 219: 44.16
+	Mm
		926536 PP1G_MOUSE (1-323): 0: 602: 99.69		BAX_MOUSE (28-198): 3.25e-51: 166: 24.14
+	Hs
		905851 PP1A_HUMAN (1-323): 0: 579: 90.66		BAX_HUMAN (28-198): 7.18e-52: 168: 22.99
+	Hs
		906060 PP1A_HUMAN (1-323): 0: 579: 90.66		B2CL2_HUMAN (6-231): 3.69e-51: 166: 39.38
+	Hs
		489398 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		BCL2_HUMAN (5-231): 3.01e-71: 219: 44.16