HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	30344098, 21382349
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 282
+	Hs
		516386 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		737785 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		737724 PP1G_HUMAN (1-323): 0: 603: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516441 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		905870 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		906041 PP1A_HUMAN (1-323): 0: 579: 90.66		PPIL4_HUMAN (117-195): 7.73e-27: 110: 39.24
+	Sp
		532280 PP11_SCHPO (7-322): 0: 555: 82.92		PABP_SCHPO (100-251): 2.84e-22: 98.3: 21.94
+	Zm
		6224 B4FJL0_MAIZE (4-314): 0: 550: 75.24		A0A1D6E6L1_MAIZE (113-267): 8.57e-22: 96.7: 22.15
+	Mm
		857299 PP1B_MOUSE (1-322): 0: 560: 86.89		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Hs
		516454 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Zm
		9804 A0A1D6QAR4_MAIZE (4-251): 1.48e-148: 419: 75.00		A0A1D6EZQ5_MAIZE (6-277): 7.27e-46: 162: 15.07