Protein: RAD52
DNA repair protein RAD52 homolog

Gene: RAD52
Organism: Homo sapiens
Interactions: 65
UniProt ID: P43351

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000730 - DNA recombinase assembly
GO:0003677 - DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

847970

RAD52
DNA repair protein RAD52 homolog

10

6

Small-scale

0.974

High

847989

RAD51
DNA repair protein RAD51 homolog 1

11

6

Small-scale

0.758

High

588121

RFA2
Replication protein A 32 kDa subunit

5

3

Small-scale

0.716

High

694841

RFA1
Replication protein A 70 kDa DNA-binding subunit

5

4

Small-scale

0.716

High

767616

RFA3
Replication protein A 14 kDa subunit

3

0

Small-scale

0.638

High

847993

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

2

0

Small-scale

0.628

High

138645

IMA4
Importin subunit alpha-4

2

1

High-throughput

0.606

High

179031

IMA6
Importin subunit alpha-6

2

1

High-throughput

0.606

High

847974

MEOX1
Homeobox protein MOX-1

2

2

High-throughput

0.606

High

847983

SUMO1
Small ubiquitin-related modifier 1

2

3

Small-scale

0.586

High

847988

PAX5
Paired box protein Pax-5

2

0

High-throughput

0.580

High

847992

NFYC
Nuclear transcription factor Y subunit gamma

2

0

High-throughput

0.580

High

847997

RDM1
RAD52 motif-containing protein 1

2

0

High-throughput

0.580

High

848002

PLK3
Serine/threonine-protein kinase PLK3

2

0

High-throughput

0.580

High

848004

DCP1A
mRNA-decapping enzyme 1A

2

0

High-throughput

0.580

High

847972

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

2

0

High-throughput

0.576

High

847998

XPF
DNA repair endonuclease XPF

1

0

Small-scale

0.561

High

464365

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.537

High

532431

CH60
60 kDa heat shock protein, mitochondrial

1

1

Small-scale

0.536

High

536685

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.536

High

687919

EF1G
Elongation factor 1-gamma

1

1

Small-scale

0.536

High

732257

PRDX2
Peroxiredoxin-2

1

2

Small-scale

0.536

High

847977

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.536

High

847979

1433E
14-3-3 protein epsilon

1

1

Small-scale

0.536

High

847982

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.536

High

847990

PRDX1
Peroxiredoxin-1

1

2

Small-scale

0.536

High

847994

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.515

High

402548

ALDOA
Fructose-bisphosphate aldolase A

1

0

Small-scale

0.513

High

408718

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

Small-scale

0.513

High

445768

ENOA
Alpha-enolase

1

0

Small-scale

0.513

High

459493

PROF1
Profilin-1

1

0

Small-scale

0.513

High

714785

EF1D
Elongation factor 1-delta

1

0

Small-scale

0.513

High

809516

RS19
Small ribosomal subunit protein eS19

1

0

Small-scale

0.513

High

847971

RS10
Small ribosomal subunit protein eS10

1

0

Small-scale

0.513

High

847976

SEC13
Protein SEC13 homolog

1

0

Small-scale

0.513

High

847980

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

Small-scale

0.513

High

847985

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.513

High

847999

DAZP1
DAZ-associated protein 1

1

0

Small-scale

0.513

High

847984

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.508

High

755528

TTK
Dual specificity protein kinase TTK

1

2

Small-scale

0.501

High

848000

AURKB
Aurora kinase B

1

1

Small-scale

0.501

High

611653

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.493

High

622773

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

Small-scale

0.493

High

847975

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

847978

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.480

High

461250

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.479

High

667204

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.479

High

669837

MCM3
DNA replication licensing factor MCM3

1

3

Small-scale

0.479

High

761574

HSP74
Heat shock 70 kDa protein 4

1

2

Small-scale

0.479

High

847973

MCM2
DNA replication licensing factor MCM2

1

3

Small-scale

0.479

High

847995

TBA1A
Tubulin alpha-1A chain

1

1

Small-scale

0.479

High

798810

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

847981

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

Small-scale

0.458

High

847991

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

848001

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

848003

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

716255

PRDX6
Peroxiredoxin-6

1

2

Small-scale

0.445

High

654098

XPA
DNA repair protein complementing XP-A cells

1

0

High-throughput

0.426

High

847987

ARF1
ADP-ribosylation factor 1

1

0

Small-scale

0.426

High

847986

TBA1B
Tubulin alpha-1B chain

1

1

Small-scale

0.407

High

450948

LDHB
L-lactate dehydrogenase B chain

1

0

Small-scale

0.279

Low

553143

KCRB
Creatine kinase B-type

1

0

Small-scale

0.279

Low

698234

MAP4
Microtubule-associated protein 4

1

0

High-throughput

0.279

Low

847996

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025