HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30344098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex GO:0044877 - protein-containing complex binding and 1 others more... GO:0051301 - cell division
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 2115
+	Xl
		193799 PP1GA_XENLA (1-323): 0: 601: 99.38		O42263_XENLA (9-1330): 1.1e-38: 162: 11.54
+	Hs
		905840 PP1A_HUMAN (1-323): 0: 579: 90.66		CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63
+	Hs
		724689 PP1G_HUMAN (1-323): 0: 603: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		737818 PP1G_HUMAN (1-323): 0: 603: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		724746 PP1A_HUMAN (1-323): 0: 579: 90.66		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		528366 PP1A_HUMAN (1-323): 0: 579: 90.66		MYH6_HUMAN (1-883): 5.66e-32: 139: 13.37
+	Mm
		906240 PP1A_MOUSE (1-323): 0: 579: 90.36		MYH6_MOUSE (1271-2077): 2.58e-31: 137: 10.66
+	Hs
		724747 PP1B_HUMAN (1-322): 0: 560: 86.89		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		906466 PP1B_HUMAN (1-322): 0: 560: 86.89		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		724764 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725131 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Dm
		404229 PP1B_DROME (1-323): 0: 552: 82.48		MYSA_DROME (478-1618): 3.93e-09: 64.3: 19.72
+	Dm
		404244 Q8T0U6_DROME (19-323): 0: 535: 83.39		MYSA_DROME (478-1618): 3.93e-09: 64.3: 19.72