Protein: ORC6
Origin recognition complex subunit 6 (ACS-associated protein 1) (Origin recognition complex 50 kDa subunit)

Gene: ORC6
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P38826

Gene Ontology (top 5):
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005664 - nuclear origin of replication recognition complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

698716

ORC2
Origin recognition complex subunit 2

11

0

Small-scale

0.929

High

755749

ORC3
Origin recognition complex subunit 3

9

0

Small-scale

0.921

High

755746

ORC5
Origin recognition complex subunit 5

7

0

Small-scale

0.915

High

667580

MCM2
DNA replication licensing factor MCM2

2

0

Small-scale

0.776

High

755748

ORC1
Origin recognition complex subunit 1

13

2

Small-scale

0.759

High

755750

ORC4
Origin recognition complex subunit 4

6

2

Small-scale

0.727

High

339619

CDK1
Cyclin-dependent kinase 1

7

0

Small-scale

0.717

High

755744

CDT1
Cell division cycle protein CDT1

6

0

Small-scale

0.699

High

673198

CGS5
S-phase entry cyclin-5

4

1

Small-scale

0.692

High

755752

CDC14
Tyrosine-protein phosphatase CDC14

4

0

Small-scale

0.676

High

447793

CDC6
Cell division control protein 6

3

2

Small-scale

0.651

High

755736

ORC6
Origin recognition complex subunit 6

3

0

Small-scale

0.630

High

755738

HAT2
Histone acetyltransferase type B subunit 2

3

0

Small-scale

0.622

High

755762

HAT1
Histone acetyltransferase type B catalytic subunit

3

0

Small-scale

0.622

High

355889

H2B2
Histone H2B.2

2

1

High-throughput

0.601

High

511248

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.576

High

355479

H2B1
Histone H2B.1

2

1

High-throughput

0.571

High

624684

CG22
G2/mitotic-specific cyclin-2

1

1

Small-scale

0.569

High

356465

H4
Histone H4

2

0

High-throughput

0.563

High

493920

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

620011

MPIP
M-phase inducer phosphatase

1

0

Small-scale

0.518

High

755764

RLF2
Chromatin assembly factor 1 subunit p90

1

0

Small-scale

0.518

High

693706

IME2
Meiosis induction protein kinase IME2/SME1

1

1

Small-scale

0.501

High

392424

H2A2
Histone H2A.2

1

0

High-throughput

0.493

High

755737

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

755747

H1
Histone H1

1

0

High-throughput

0.493

High

755753

HMO1
High mobility group protein 1

1

0

High-throughput

0.493

High

755757

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.493

High

755759

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

744580

PCH2
Pachytene checkpoint protein 2

1

0

Small-scale

0.480

High

523379

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.460

High

608744

CHL1
ATP-dependent DNA helicase CHL1

1

0

Small-scale

0.460

High

687532

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.460

High

755756

NOC3
Nucleolar complex-associated protein 3

1

0

Small-scale

0.460

High

755760

PKH2
Serine/threonine-protein kinase PKH2

1

0

High-throughput

0.460

High

634596

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

755741

FKH1
Fork head protein homolog 1

1

0

Small-scale

0.458

High

755751

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

Small-scale

0.458

High

755754

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

755763

PSF1
DNA replication complex GINS protein PSF1

1

0

Small-scale

0.458

High

491162

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

694662

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

633209

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

733245

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

755740

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

755745

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

478174

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.407

High

755739

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.407

High

755743

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

755755

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.407

High

733819

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.269

Low

752310

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

755758

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

368039

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

424508

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

543697

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

705153

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

755742

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

755761

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024